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HemaFus ETV6-RUNX1 Fusion Gene Quantitative Detection Kit (PCR-Fluorescent Probing)
HemaFus ETV6-RUNX1融合基因定量检测试剂盒(PCR-荧光探针法)_3504x2613

HemaFus ETV6-RUNX1 Fusion Gene Quantitative Detection Kit (PCR-Fluorescent Probing)

Product introduction The ETV6-RUNX1 fusion gene is quantitatively detected by fluorescence quantitative PCR.Cat.
Cat. No.:
T0309
Spec:
24 Tests/Kit
HemaFus ETV6-RUNX1融合基因定量检测试剂盒(PCR-荧光探针法)_3504x2613
Product description
Parameters

Background

 

The ETV6-RUNX1 (TEL-AML1) fusion gene, formed by the t(12;21)(p13;q22) translocation (Figure 1), is the most frequent abnormality in childhood ALL (approx. 25% of childhood B-ALL), and t (12;21) has not been found in T-ALL, AML, or NHL so far, even rarely reported in infant leukemia, and much rarer in adult leukemia (< 2%). The ETV6-RUNX1 fusion gene is an independent prognostic factor, and such patients respond well to treatment, with a long duration of complete remission and good prognosis.

 

 

Figure 1

 

 

Features

 

Simple operation and less time consumption; reliable results and intuitive interpretation; high sensitivity and sample saving.

 

 

Detection Process

 

In this method, RNA is isolated and purified from leukocytes in peripheral blood or bone marrow samples, and cDNA is obtained by reverse transcription to quantitatively detect the ETV6-RUNX1 fusion gene by fluorescence quantitative PCR.
The fusion of fusion genes is shown in Figure 2.

 

Figure 2

 

 

Applicable instrument

 

ABI fluorescence quantitative PCR system (ABI7500, ABI ViiA7)

 

 

Ordering Information

 

Cat. No. Product Strength
J0369 HemaFus ETV6-RUNX1 Fusion Gene Qualitative Detection Kit
(PCR-Fluorescent Probing)
24 Tests/Kit
T0309 HemaFus ETV6-RUNX1 Fusion Gene Quantitative Detection Kit
(PCR-Fluorescent Probing)
24 Tests/Kit

 

 

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Copyright:Wuhan Healthy Biotechnology Co., Ltd.