Products
HemaSeq Human 260 Gene Mutation Detection Kit （NGS-for Illumina）
Cat. No.:
S0868-S
Spec:
6 rxns/Kit（60 Tests）
Product description
Parameters
Detection Content
NGS technology enables the detection of mutations in 260 gene associated with various signaling pathways involved in B-cell lymphoma pathogenesis, which can assist in the diagnosis, differential diagnosis, prognosis and treatment (see the gene list for details).
Advantages
1. Covers related genes on various signaling pathways of pathogenesis and key genes in WHO, NCCN, guidelines of Chinese Society of Clinical Oncology (CSCO) lymphoid malignancies, Chinese guidelines for diagnosis and treatment of B-cell lymphoma subtypes, expert consensuses and authoritative literature to assist clinical decision-making and meet scientific research needs.
2. Covers library preparation reagents, hybrid capture reagents, and probes for 260 genes in Kit components (of which BCL2, BCL6, and MYC genes include common fusion genes and some chemotherapy-related SNP sites);
3. flexible with Illumina and ThermoFisher sequencing platforms.
4. High sensitivity, with accurate and stable detection of 1% mutation frequency.
Target Population
To meet the clinical needs of B-cell lymphoma, a gene detection panel has been designed specifically for clinical use. This panel is informed by the NCCN guidelines, WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues (2008 and 2016 revisions), guidelines of the Chinese Society of Clinical Oncology (CSCO) for lymphoid malignancies, Chinese guidelines for diagnosis and treatment of B-cell lymphoma subtypes, expert consensuses, authoritative classics, and the latest literature. The resulting gene panel is tailored to the actual clinical needs of practitioners, ensuring that it assists with disease diagnosis, differential diagnosis, prognosis, and treatment. This panel is applicable to patients with CLL/SLL, DLBCL, FL, BL, MCL, MZL, HCL, WM, and other common B-cell lymphoma.
Gene List (only partial genes displayed)
|
ACTB |
ARID1A |
KDM6A |
KRAS |
BCL10 |
BRAF |
|
ACTG1 |
ARID1B |
KDR |
LRP1B |
BCL11A |
BTG1 |
|
ADCYAP1 |
ARID2 |
KIAA1614 |
LYN |
BCL2 |
BTG2 |
|
AKT1 |
ATM |
KIF1C |
MAP2K1 |
BCL2L1 |
BTK |
|
ALDH18A1 |
ATP6AP1 |
KLF2 |
MAP3K14 |
BCL6 |
LCOR |
|
ALDH3A2 |
ATP6AP2 |
KLHL14 |
MAP3K7 |
BCL7A |
CAMK2A |
|
ALK |
ATP6V0A1 |
KLHL6 |
MAPK1 |
BCOR |
CARD11 |
|
AMOTL1 |
ATP6V1B2 |
KMT2A |
MCL1 |
BIRC3 |
CASP10 |
|
ANKRD17 |
ATP6V1F |
KMT2C |
B2M |
BIRC6 |
CBFA2T3 |
|
APC |
JUNB |
KMT2D |
ADGRB1 |
BMI1 |
CCND1 |
Ordering Information
| Cat. No. | Product | Strength |
| S0868-S |
HemaSeq Human 260 Gene Mutation Detection Kit
|
6 rxns/Kit （60 Tests） |
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